Research Article

Predictors of Nonsentinel Nodal Involvement to Aid Intraoperative Decision Making in Breast Cancer Patients with Positive Sentinel Lymph Nodes

Table 1

Correlation analyses of SLN involvement and clinicopathological parameters ( š‘› = 1 1 0 ).

Patients with SLN positive only
( š‘› = 6 0 )
Patients with non-SLN involvement ( š‘› = 5 0 ) š‘ƒ value

Median age (years)54.0 (37.0 to 80.0)51.5 (30.0 to 77.0)0.42
Ethnicity0.70
ā€ƒChinese4736
ā€ƒMalay88
ā€ƒIndian24
ā€ƒOthers32
Family history of breast cancer0.53
ā€ƒYes78
ā€ƒNo5242
Tumour histology0.20
ā€ƒIDC5642
ā€ƒILC47
Median tumour size (mm)20.0 (4.0 to 80.0)24.5 (1.0 t o 55.0)0.03
Tumour grade0.99
ā€ƒ156
ā€ƒ22819
ā€ƒ32623
Lymphovascular invasion0.81
ā€ƒPresent2622
ā€ƒAbsent2927
Associated DCIS0.97
ā€ƒEIC108
ā€ƒDCIS2519
ā€ƒNone2217
Oestrogen receptor status0.84
ā€ƒPositive4235
ā€ƒNegative1713
Progesterone receptor status0.42
ā€ƒPositive3121
ā€ƒNegative2826
HER2 status0.16
ā€ƒPositive1610
ā€ƒNegative2733
Size of nodal disease0.01
ā€ƒMacrometastases4649
ā€ƒMicrometastases141
Ratio of positive SLN to total SLN harvested0.01
ā€ƒ<0.5208
ā€ƒ0.5 to 1148
ā€ƒ12634
Number of axillary nodes0.03
ā€ƒ<10113
ā€ƒ10 to 202516
ā€ƒ20 to 301724
ā€ƒ>3077
Distant recurrence0.34
ā€ƒYes57
ā€ƒNo5543
Median Tenon score5.0 (1.5 to 7.0)5.75 (2 to 7)<0.001
Median MSKCC probability19.5 (3.0 to 74.0)41.0 (6.0 to 89.0)<0.001