Research Article
Predictors of Nonsentinel Nodal Involvement to Aid Intraoperative Decision Making in Breast Cancer Patients with Positive Sentinel Lymph Nodes
Table 1
Correlation analyses of SLN involvement and clinicopathological parameters ().
| | Patients with SLN positive only () | Patients with non-SLN involvement () | value |
| Median age (years) | 54.0 (37.0 to 80.0) | 51.5 (30.0 to 77.0) | 0.42 | Ethnicity | | | 0.70 | āChinese | 47 | 36 | | āMalay | 8 | 8 | | āIndian | 2 | 4 | | āOthers | 3 | 2 | | Family history of breast cancer | | | 0.53 | āYes | 7 | 8 | | āNo | 52 | 42 | | Tumour histology | | | 0.20 | āIDC | 56 | 42 | | āILC | 4 | 7 | | Median tumour size (mm) | 20.0 (4.0 to 80.0) | 24.5 (1.0 t o 55.0) | 0.03 | Tumour grade | | | 0.99 | ā1 | 5 | 6 | | ā2 | 28 | 19 | | ā3 | 26 | 23 | | Lymphovascular invasion | | | 0.81 | āPresent | 26 | 22 | | āAbsent | 29 | 27 | | Associated DCIS | | | 0.97 | āEIC | 10 | 8 | | āDCIS | 25 | 19 | | āNone | 22 | 17 | | Oestrogen receptor status | | | 0.84 | āPositive | 42 | 35 | | āNegative | 17 | 13 | | Progesterone receptor status | | | 0.42 | āPositive | 31 | 21 | | āNegative | 28 | 26 | | HER2 status | | | 0.16 | āPositive | 16 | 10 | | āNegative | 27 | 33 | | Size of nodal disease | | | 0.01 | āMacrometastases | 46 | 49 | | āMicrometastases | 14 | 1 | | Ratio of positive SLN to total SLN harvested | | | 0.01 | ā<0.5 | 20 | 8 | | ā0.5 to 1 | 14 | 8 | | ā1 | 26 | 34 | | Number of axillary nodes | | | 0.03 | ā<10 | 11 | 3 | | ā10 to 20 | 25 | 16 | | ā20 to 30 | 17 | 24 | | ā>30 | 7 | 7 | | Distant recurrence | | | 0.34 | āYes | 5 | 7 | | āNo | 55 | 43 | | Median Tenon score | 5.0 (1.5 to 7.0) | 5.75 (2 to 7) | <0.001 | Median MSKCC probability | 19.5 (3.0 to 74.0) | 41.0 (6.0 to 89.0) | <0.001 |
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