Table of Contents
ISRN Dentistry
Volume 2011, Article ID 541421, 6 pages
Research Article

Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens—An In Vitro Study

1Department of Plant Biology and Biotechnology, School of Life Sciences, Loyola College, Chennai 600 034, India
2Department of Conservative Dentistry and Endodontics, R.M.D.C.H., Annamalai University, Annamalai Nagar, Chidambaram, Pin code-608002, India

Received 4 April 2011; Accepted 3 May 2011

Academic Editors: M. H. Parkar and S. L. Yankell

Copyright © 2011 H. Shyla Jebashree et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hexane, ethyl acetate, ethanol and methanol extracts of Psidium guajava, Terminalia chebula, Mimusops elengi and Achyranthes aspera were tested against the dental caries causing bacteria Streptococcus mutans and fungus Candida albicans isolated from caries infected patients. All the four extracts of P. guajava showed activity against both S. mutans and C. albicans. Maximum zone of inhibition was observed in ethyl acetate of P. guajava. The four extracts of T. chebula and M. elengi showed antibacterial activity against S. mutans. M. elengi extracts and ethanol extract of T. chebula did not show any antifungal activity against C. albicans. Except for the hexane extract of A. aspera, the other three extracts showed activity against the tested microbes. The ethyl acetate P. guajava leaf extract showed the minimum inhibitory concentration (MIC) against S. mutans to be <0.076 mg/mL in both MHB and BHI. The P. guajava ethyl acetate extract was subjected to GC-MS.