Table of Contents
ISRN Veterinary Science
Volume 2011, Article ID 560905, 6 pages
http://dx.doi.org/10.5402/2011/560905
Research Article

Genetic Characterization of Porcine Circovirus Type 2 from Pigs with Porcine Circovirus Associated Diseases in Argentina

1Laboratorio Aves y Porcinos, Instituto de Virologia CICVyA, Instituto Nacional de Tecnologia Agropecuaria (INTA), CC25, 1712 Castelar, Buenos Aires, Argentina
2Cátedra de Patología Especial, Departamento de Ciencias Pre-clínicas, Facultad de Ciencias, Veterinarias, Universidad Nacional de La Plata, Casilla de Correo N°296, Calle 60 y 118 S/N, 1900 La Plata, Buenos Aires, Argentina
3Area de Virología, Facultad de Ciencias, Veterinarias, Universidad de Buenos Aires, Chorroarín 280, C1427CWO CABA, Argentina
4Servicio Nacional de Sanidad y Calidad Agroalimentaria, Dirección de Laboratorio Animal, Avenida Fleming 1653, 1640 Martínez, Buenos Aires, Argentina

Received 4 March 2011; Accepted 5 April 2011

Academic Editors: M. Benko, R. Thanawongnuwech, and S. Vilcek

Copyright © 2011 Ariel Pereda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. I. Tischer, H. Gelderblom, W. Vettermann, and M. A. Koch, “A very small porcine virus with circular single-stranded DNA,” Nature, vol. 295, no. 5844, pp. 64–66, 1982. View at Google Scholar · View at Scopus
  2. “The circoviridae,” in Virus Taxonomy Sixth Report of the International Committee on Taxonomy of Viruses, P. Lukert, G. F. De Boer, J. L. Dale et al., Eds., pp. 166–168, Springer, Vienna, Austria, 1995.
  3. B. M. Meehan, J. L. Creelan, M. S. McNulty, and D. Todd, “Sequence of porcine circovirus DNA: affinities with plant circovirses,” Journal of General Virology, vol. 78, no. 1, pp. 221–227, 1997. View at Google Scholar · View at Scopus
  4. I. Tischer, R. Rasch, and G. Tochtermann, “Characterization of papovavirus and picornavirus like particles in permanent pig kidney cell lines,” Zentralblatt für Bakteriologie, vol. 226, no. 2, pp. 153–167, 1974. View at Google Scholar · View at Scopus
  5. J. C. Harding, “Post-weaning multisystemic wasting syndrome (PMWS): preliminary epidemiology and clinical presentation,” in Proceedings of the 27th Annual Meeting Western Canadian Association of Swine Practitioners, p. 21, Saskatoon, Canada, October 1996.
  6. J. Ellis, S. Krakowka, M. Lairmore et al., “Reproduction of lesions of postweaning multisystemic wasting syndrome in gnotobiotic piglets,” Journal of Veterinary Diagnostic Investigation, vol. 11, no. 1, pp. 3–14, 1999. View at Google Scholar · View at Scopus
  7. J. Segales, M. Domingo, and K. S. Latimer, “Porcine circovirus is present in cases of porcine dermatitis and nephropathy syndrome (PDNS),” in Proceedings of the 15th International Pig Veterinary Society Congress, p. 215, Birmingham, UK, 1998.
  8. J. Segales, C. Rosell, and M. Domingo, “Pathological findings associated with naturally acquired porcine circovirus type 2 associated disease,” Veterinary Microbiology, vol. 98, no. 2, pp. 137–149, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. R. Cariolet, B. Blanchard, M. Le Dimna et al., “Consequences of PCV-2 experimental infection of non immune SPF sows using the intrauterine route,” in Proceedings of the International Conference on ssDNA Viruses of Plants, Birds and Primates, p. 129, Saint-Malo, France, 2001.
  10. T. Opriessnig, X. J. Meng, and P. G. Halbur, “Porcine circovirus type 2-associated disease: update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies,” Journal of Veterinary Diagnostic Investigation, vol. 19, no. 6, pp. 591–615, 2007. View at Google Scholar · View at Scopus
  11. J. Sarradell, A. M. Perez, M. Andrada, F. Rodriguez, A. Fernandez, and J. Segales, “PMWS in Argentina,” Veterinary Record, vol. 150, no. 10, p. 323, 2002. View at Google Scholar · View at Scopus
  12. J. C. Harding and E. G. Clark, “Recognizing and diagnosing postweaning multisystemic wasting syndrome (PMWS),” Journal of Swine Health and Production, vol. 5, no. 5, pp. 201–203, 1997. View at Google Scholar
  13. C. Rosell, J. Segales, J. Plana-Duran et al., “Pathological, immunohistochemical, and in-situ hybridization studies of natural cases of postweaning multisystemic wasting syndrome (PMWS) in pigs,” Journal of Comparative Pathology, vol. 120, no. 1, pp. 59–78, 1999. View at Publisher · View at Google Scholar · View at Scopus
  14. A. Mankertz, R. Caliskan, K. Hattermann et al., “Molecular biology of Porcine circovirus: analyses of gene expression and viral replication,” Veterinary Microbiology, vol. 98, no. 2, pp. 81–88, 2004. View at Publisher · View at Google Scholar · View at Scopus
  15. A. Olvera, M. Cortey, and J. Segales, “Molecular evolution of porcine circovirus type 2 genomes: phylogeny and clonality,” Virology, vol. 357, no. 2, pp. 175–185, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. L. Grau-Roma, E. Crisci, M. Sibila et al., “A proposal on porcine circovirus type 2 (PCV2) genotype definition and their relation with postweaning multisystemic wasting syndrome (PMWS) occurrence,” Veterinary Microbiology, vol. 128, no. 1-2, pp. 23–35, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Segalés, A. Olvera, L. Grau-Roma et al., “PCV-2 genotype definition and nomenclature,” Veterinary Record, vol. 162, no. 26, pp. 867–868, 2008. View at Google Scholar · View at Scopus
  18. W. Cui, G. Xin, X. Ge, and H. Yang, “Genotype analysis of Chinese porcine circovirus type 2 in 2008-2009,” in Proceedings of the 21st International Pigs Veterinary Society Congress, p. 322, Vancouver, Canada, 2010.
  19. C. A. Gagnon, D. Tremblay, P. Tijssen, M. H. Venne, A. Houde, and S. M. Elahi, “The emergence of porcine circovirus 2b genotype (PCV-2b) in swine in Canada,” Canadian Veterinary Journal, vol. 48, no. 8, pp. 811–819, 2007. View at Google Scholar · View at Scopus
  20. A. K. Cheung, K. M. Lager, O. I. Kohutyuk et al., “Detection of two porcine circovirus type 2 genotypic groups in United States swine herds,” Archives of Virology, vol. 152, no. 5, pp. 1035–1044, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. M. De Castro, A. Cortez, M. B. Heinemann, P. E. Brandao, and L. J. Richtzenhain, “Genetic diversity of Brazilian strains of porcine circovirus type 2 (PCV-2) revealed by analysis of the cap gene (ORF-2),” Archives of Virology, vol. 152, no. 8, pp. 1435–1445, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. J. R. Ciacci-Zanella, N. L. Simon, L. S. Pinto et al., “Detection of porcine Circovirus type 2 (PCV2) variants PCV2-1 and PCV2-2 in Brazilian pig population,” Research in Veterinary Science, vol. 87, no. 1, pp. 157–160, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Fort, A. Olvera, M. Sibila, J. Segales, and E. Mateu, “Detection of neutralizing antibodies in postweaning multisystemic wasting syndrome (PMWS)-affected and non-PMWS-affected pigs,” Veterinary Microbiology, vol. 125, no. 3-4, pp. 244–255, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. J. D. Thompson, D. G. Higgins, and T. J. Gibson, “CLUSTAL W: improving the sensitivity of progressive nultiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice,” Nucleic Acids Research, vol. 22, no. 22, pp. 4673–4680, 1994. View at Google Scholar
  25. J. Felsenstein, “PHYLIP* phylogeny interference package (version 3.2),” Cladistics, vol. 5, pp. 164–166, 1989. View at Google Scholar
  26. D. M. Hillis and J. J. Bull, “An empirical test of bootstrapping as a method for assessing confidence in phylogenetic analysis,” Systematic Biology, vol. 42, no. 2, pp. 182–192, 1993. View at Google Scholar · View at Scopus
  27. R. D. page, “Treeview: an application to display phylogenetic trees on personal computers,” Computer Applications in the Biosciences, vol. 12, no. 4, pp. 357–358, 1996. View at Google Scholar · View at Scopus
  28. D. D. Wiederkehr, T. Sydler, E. Brugnera, A. Pospischil, E. Buergi, and X. Sidler, “Pathogenic differences of porcine circovirus type 2 genotypes in Switzerland,” in Proceedings of the 20th International Pigs Veterinary Society Congress, p. 26, Durban, South Africa, 2008.
  29. J. C. Harding, J. A. Ellis, K. A. McIntosh, and S. Krakowka, “Dual heterologous porcine circovirus genogroup 2a/2b infection induces severe disease in germ-free pigs,” Veterinary Microbiology, vol. 145, no. 3-4, pp. 209–219, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. K. M. Lager, P. C. Gauger, A. L. Vincent, T. Opriessnig, M. E. Kehrli Jr., and A. K. Cheung, “Mortality in pigs given porcine circovirus type 2 subgroup 1 and 2 viruses derived from DNA clones,” Veterinary Record, vol. 161, no. 12, pp. 428–429, 2007. View at Google Scholar · View at Scopus
  31. T. Opriessnig, J. R. Prickett, D. M. Madson et al., “Porcine circovirus type 2 (PCV2)-infection and re-inoculation with homologous or heterologous strains: virological, serological, pathological and clinical effects in growing pigs,” Veterinary Research, vol. 41, no. 3, p. 31, 2010. View at Publisher · View at Google Scholar · View at Scopus
  32. J. S. Chae and K. S. Choi, “Genetic diversity of porcine circovirus type 2 from pigs in Republic of Korea,” Research in Veterinary Science, vol. 88, no. 2, pp. 333–338, 2010. View at Publisher · View at Google Scholar · View at Scopus