Research Article

Results of a Pilot Randomized Placebo-Controlled Trial in Primary and Secondary Raynaud's Phenomenon with St. John's Wort: Detecting Changes in Angiogenic Cytokines When RP Improves

Table 1

Within-group characteristics for frequency, duration, and severity of RP in SJW compared to placebo in the completers. There were no between-group differences.

Baseline SJW ( 𝑁 = 8 )6-Week Followup SJWMean difference SJW 𝑃 -value Within group SJWBaseline Placebo ( 𝑁 = 1 0 )6-Week Followup PlaceboMean difference Placebo 𝑃 -value Within group Placebo

Frequency (mean no. of attacks per day)3.1752.4238.75130.12382.3661.3531.01300.001
Duration (mean total of attacks in minutes per day)28.27918.00910.27030.001926.01013.51012.49920.009
Severity (scale 0 to 10)4.7523.785.96680.07582.9541.9471.00660.004