Table of Contents
ISRN Oncology
Volume 2011 (2011), Article ID 617593, 13 pages
http://dx.doi.org/10.5402/2011/617593
Review Article

Review of Breast Conservation Therapy: Then and Now

1Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
2Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
3Department of General Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA

Received 1 April 2011; Accepted 11 May 2011

Academic Editor: Y. Yamamoto

Copyright © 2011 Susan Hoover et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Breast conservation therapy (BCT), which is the marriage of breast conserving surgery and radiation therapy to the breast, has revolutionized the treatment of breast cancer over the last few decades. Surgical direction had seen a heightened interest in the performance of cosmetically superior partial and segmental resections in breast conservation as well as increased demand by patients for breast preservation. The broadening of approaches to delivery of breast irradiation from whole breast to accelerated partial breast has allowed more patients to opt for breast conservation and allowed for what appears to be comparable measurable outcomes in emerging data. As well, the addition of state-of-the-art chemotherapeutic and hormonal therapies has allowed improved outcomes of patients from both local regional recurrence and overall survival standpoints. This paper will provide an overview of BCT and review some of the newest developments in optimizing this therapy for patients with breast cancer from a surgical-, medical-, and radiation-oncology standpoint.