Prognostic Significance of the Number of Removed and Metastatic Lymph Nodes and Lymph Node Ratio in Breast Carcinoma Patients with 1–3 Axillary Lymph Node(s) Metastasis

Table 4

Cox proportional hazards model analysis of the clinicopathological features and lymph node ratio in terms of distant metastasis-free survival in the whole series.

Feature	Relative risk	%95 CI	P
Age, years			0.009
<35	1.00
≥35	0.58	0.39–0.87
Menopausal status			0.148
Premenopausal	1.00
Postmenopausal	0.80	0.60–1.08
Tumor size			<0.001
T1	1.00
T2	2.13	1.53–2.97
T3	2.94	1.92–4.51
Histological type			0.042
Invasive ductal	1.00
Invasive lobular	1.08	0.68–1.71
Invasive ductal and lobular	1.50	0.85–2.64
Other	0.24	0.07–0.75
Adjuvant chemotherapy			0.986
Yes	1.00
No	1.00	0.63–1.58
Adjuvant hormonal therapy			0.016
Yes	1.00
No	1.39	1.06–1.82
Adjuvant radiotherapy			0.037
Yes	1.00
No	1.47	1.02–2.12
Lymph node ratio			<0.001
≤0.15	1.00
>0.15	1.72	1.33–2.23