Formulation and Evaluation of Transdermal Patch of Repaglinide

Table 2

Formulation and evaluation of 3² full factorial design batches.

Batch code	𝑋1 (HPMC grade)	𝑋2 (% PVP K30 concentration)	𝑌1 (tensile strength kg/cm^2)	𝑌2 (𝑄1)(%)	𝑌3 (𝑄9)(%)	𝑌4 (diffusion coefficient)
F1	HPMC E15 LV	0.5	0.38	9.780612	88.91582	1.043
F2	HPMC E15 LV	1	0.46	11.31122	90.59949	1.001
F3	HPMC E15 LV	1.5	0.63	12.22959	98.26531	0.983
F4	HPMC K100	0.5	0.45	13.30102	54.54082	0.665
F5	HPMC K100	1	0.58	13.91327	63.78827	0.746
F6	HPMC K100	1.5	0.92	18.96429	75.90561	0.641
F7	HPMC K4M	0.5	0.53	7.331633	48.52041	0.959
F8	HPMC K4M	1	0.84	8.862245	37.98469	0.656
F9	HPMC K4M	1.5	0.95	9.627551	57.70408	0.853