Research Article

Formulation and Evaluation of Transdermal Patch of Repaglinide

Table 4

Evaluation parameters of factorial batches F1 to F9.

Sr. no.Batch codeFolding enduranceTensile strength (kg/cm2) (mean ± S.D.)% Elongation
(Mean ± S.D.)
Thickness (mm) (mean ± S.D.)% Drug content (mean ± S.D.) 𝑓 2 value

1F1 < 1 5 0 0 . 3 8 ± 0 . 0 1 5 4 1 . 2 ± 0 . 0 1 5 0 . 1 2 ± 0 . 0 2 5 78.98 52.58
2F2 < 1 5 0 0 . 4 6 ± 0 . 0 1 2 3 8 . 8 ± 0 . 0 1 4 0 . 1 5 ± 0 . 0 6 2 78.941 49.97
3F3 > 2 0 0 0 . 6 3 ± 0 . 0 1 5 3 7 . 1 ± 0 . 0 1 2 0 . 2 5 ± 0 . 0 2 2 78.63 45.44
4F4 > 2 0 0 0 . 4 5 ± 0 . 0 1 4 4 0 . 2 ± 0 . 0 1 3 0 . 2 2 ± 0 . 0 1 2 77.851 31.38
5F5 > 2 0 0 0 . 5 8 ± 0 . 0 1 5 3 9 . 6 ± 0 . 0 1 7 0 . 1 5 ± 0 . 0 1 5 78.327 44.75
6F6 > 2 0 0 0 . 9 2 ± 0 . 0 1 7 3 5 . 8 ± 0 . 0 1 2 0 . 1 7 ± 0 . 0 1 3 77.956 69.18
7F7 > 2 0 0 0 . 5 3 ± 0 . 0 1 1 3 9 . 2 ± 0 . 0 1 3 0 . 1 6 ± 0 . 0 2 1 75.829 26.13
8F8 > 2 0 0 0 . 8 4 ± 0 . 0 1 7 2 8 . 9 ± 0 . 0 1 5 0 . 1 3 ± 0 . 0 1 8 74.683 23.09
9F9 > 2 0 0 0 . 9 5 ± 0 . 0 1 5 3 0 . 1 ± 0 . 0 1 5 0 . 2 3 ± 0 . 0 1 5 74.282 34.03

Values expressed as mean ± S.D, 𝑛 = 3 .