Research Article

Formulation and Evaluation of Transdermal Patch of Repaglinide

Table 5

Summary of results of regression analysis.

Tensile strength
Response 𝑏 0 𝑏 1 𝑏 2 𝑏 1 2 𝑏 2 1 𝑏 2 2
(tensile strength)

FM 0.638889 0.141667 0.19 0.0425 −0.01833 0.016667
RM 0.637778 0.141667 0.19

𝑄 1  hr
Response ( 𝑄 1 ) 𝑏 0 𝑏 1 𝑏 2 𝑏 1 2 𝑏 2 1 𝑏 2 2

FM 15.05272 −1.25 1.734694 −0.038 −5.53572 0.510204
RM 15.39286 −5.53572

𝑄 9  hr
Response ( 𝑄 9 ) 𝑏 0 𝑏 1 𝑏 2 𝑏 1 2 𝑏 2 1 𝑏 2 2

FM 60.39966 −22.2619 6.649658 −0.041 5.586733 6.517858
RM 68.46939 −22.2619

Diffusion coefficient
Response 𝑏 0 𝑏 1 𝑏 2 𝑏 1 2 𝑏 2 1 𝑏 2 2
(diffusion coefficient)

FM 0.64641 −0.09322 −0.03172 −0.011 0.231885 0.056385
RM

FM: full model, RM: reduce model.