Clinical Study

Osteoporosis and Bisphosphonate-Related Osteonecrosis of the Jaw Bone

Table 1

Patients’ characteristics, osteonecrosis of the jaw and dental treatments.

Total ( 𝑁 = 7 6 )
𝑛 (%)

Age category
 50–6014 (18.4)
 61–7027 (35.5)
 71–7928 (36.9)
 80+7 (9.2)
Median (IQR)69 (62–74)

Smoking status
 Never56 (73.7)
 Current9 (11.8)
 Former11 (14.5)

Medical history

Hypertension
 No50 (65.8)
 Yes26 (34.2)

Cardiovascular disease
 No60 (78.9)
 Yes16 (21.1)

Immunosuppressant
 No72 (94.7)
 Yes4 (5.3)

Previous radio/chemotherapy
 No73 (96.1)
 Yes3 (3.9)

BPs and BRONJ

BPs treatment
 Alendronate47 (61.8)
 Clodronate16 (21.1)
 Ibandronate3 (3.9)
 Risedronate10 (13.2)

ONJ at first visit
 No69 (90.8)
 Yes7 (9.2)

ONJ Stage
 057 (89.1)
 I3 (4.7)
 II4 (6.3)

ONJ Site
 Maxilla1 (14.3)
 Jaw Bone6 (85.7)

Oral care

Minor ONJ surgery
 No72 (94.7)
 Yes4 (5.3)

Dental treatment
 No31 (40.8)
 Yes45 (59.2)

ONJ: Osteonecrosis of the jaw; BPs: Bisphosphonates.