Table of Contents
ISRN Obstetrics and Gynecology
Volume 2011, Article ID 683020, 4 pages
Case Report

Primary Malignant Melanoma of the Uterine Cervix Treated with Ultraradical Surgery: A Case Report

1Department of Gynecologic Oncology, Instituto Nacional de Cancerologia, 14080 Mèxico, Mexico
2Department of Pathology, Instituto Nacional de Cancerologia, 14080 Mèxico, Mexico
3Department of Surgery, Instituto Nacional de Cancerologia, 14080 Mèxico, Mexico
4Department of Medical Oncology, Instituto Nacional de Cancerologia, 14080 Mèxico, Mexico

Received 22 August 2010; Accepted 8 September 2010

Academic Editors: R. M. Austin, R.-J. Chen, E. Petru, and L. B. Twiggs

Copyright © 2011 Luz Calderón-Salazar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary melanomas of the uterine cervix are rare tumors with no more than 60 cases reported in the world literature. Poor prognosis is considered for the neoplasia itself as well as for diagnostic tardiness. There is no standard treatment; however, radical surgery is the treatment cornerstone. Our aim was to present the case of a 34-year-old woman with a primary malignant melanoma in the uterine cervix with affectation of the posterior face of the vagina without metastasis. Total infraelevator pelvic exenteration and adjuvant radiotherapy was performed. The patient was under surveillance for 8 years of followup without evidence of local or distant disease. The majority of case reports found suggests radical hysterectomy as the treatment indicated for these patients. Notwithstanding this, survival is very short when patients are treated in this manner. Based on our results and on those reported in the literature, we propose initial treatment with total pelvic exenteration as optimal management for this neoplasia in its initial form.