Table of Contents
ISRN Obstetrics and Gynecology
Volume 2011 (2011), Article ID 692858, 5 pages
http://dx.doi.org/10.5402/2011/692858
Research Article

Regulatory Effect of Peptidoglycan on the Expression of Toll-Like Receptor 2 mRNA and Proteins in Trophoblast Cell Line TEV-1 Cells

1Department of Gynaecology, Guangdong Women and Children's Hospital and Health Institute, Guangzhou, 510010, China
2South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales, P.O. Box 3256, Blakehurst, Sydney NSW 2221, Australia
3Faculty of Medicine, University of New South Wales, Sydney NSW 2052, Australia
4Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430074, China

Received 28 August 2010; Accepted 21 September 2010

Academic Editors: E. G. Olivares and K. Yang

Copyright © 2011 Yi Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. Von Dadelszen and L. A. Magee, “Could an infectious trigger explain the differential maternal response to the shared placental pathology of preeclampsia and normotensive intrauterine growth restriction?” Acta Obstetricia et Gynecologica Scandinavica, vol. 81, no. 7, pp. 642–648, 2002. View at Publisher · View at Google Scholar · View at Scopus
  2. L. F. Gonçalves, T. Chaiworapongsa, and R. Romero, “Intrauterine infection and prematurity,” Mental Retardation and Developmental Disabilities Research Reviews, vol. 8, no. 1, pp. 3–13, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. R. Romero, T. Chaiworapongsa, and J. Espinoza, “Micronutrients and intrauterine infection, preterm birth and the fetal inflammatory response syndrome,” Journal of Nutrition, vol. 133, no. 5, article 1668S, 2003. View at Google Scholar
  4. R. Medzhitov and C. A. Janeway Jr., “Decoding the patterns of self and nonself by the innate immune system,” Science, vol. 296, no. 5566, pp. 298–300, 2002. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. H. Häcker, V. Redecke, B. Blagoev et al., “Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6,” Nature, vol. 439, no. 7073, pp. 204–207, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. T. Kaisho and S. Akira, “Toll-like receptor function and signaling,” Journal of Allergy and Clinical Immunology, vol. 117, no. 5, pp. 979–987, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  7. S. Akira and K. Takeda, “Toll-like receptor signalling,” Nature Reviews Immunology, vol. 4, no. 7, pp. 499–511, 2004. View at Google Scholar · View at Scopus
  8. J. C. Roach, G. Glusman, L. Rowen et al., “The evolution of vertebrate Toll-like receptors,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 27, pp. 9577–9582, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  9. T.-H. Chuang and R. J. Ulevitch, “Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9,” European Cytokine Network, vol. 11, no. 3, pp. 372–378, 2000. View at Google Scholar · View at Scopus
  10. K. A. Zarember and P. J. Godowski, “Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines,” Journal of Immunology, vol. 168, no. 2, pp. 554–561, 2002. View at Google Scholar · View at Scopus
  11. O. Thellin, B. Coumans, W. Zorzi, A. Igout, and E. Heinen, “Tolerance to the foeto-placental ‘graft’: ten ways to support a child for nine months,” Current Opinion in Immunology, vol. 12, no. 6, pp. 731–737, 2000. View at Publisher · View at Google Scholar · View at Scopus
  12. B. A. Croy, S. Chantakru, S. Esadeg, A. A. Ashkar, and Q. Wei, “Decidual natural killer cells: key regulators of placental development (a review),” Journal of Reproductive Immunology, vol. 57, no. 1-2, pp. 151–168, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. H. C. Feng, M. Y. Choy, W. Deng et al., “Establishment and characterization of a human first-trimester extravillous trophoblast cell line (TEV-1),” Journal of the Society for Gynecologic Investigation, vol. 12, no. 4, pp. e21–e32, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. Y. M. Kim, R. Romero, T. Chaiworapongsa et al., “Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis,” American Journal of Obstetrics and Gynecology, vol. 191, no. 4, pp. 1346–1355, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  15. H. Uronen-Hansson, J. Allen, M. Osman, G. Squires, N. Klein, and R. E. Callard, “Toll-like receptor 2 (TLR2) and TLR4 are present inside human dendritic cells, associated with microtubules and the Golgi apparatus but are not detectable on the cell surface: integrity of microtubules is required for interleukin-12 production in response to internalized bacteria,” Immunology, vol. 111, no. 2, pp. 173–178, 2004. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  16. U. Holmlund, G. Cebers, A. R. Dahlfors et al., “Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta,” Immunology, vol. 107, no. 1, pp. 145–151, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. V. M. Abrahams, P. Bole-Aldo, Y. M. Kim et al., “Divergent trophoblast responses to bacterial products mediated by TLRs,” Journal of Immunology, vol. 173, no. 7, pp. 4286–4296, 2004. View at Google Scholar · View at Scopus