Table of Contents
ISRN Oncology
Volume 2011, Article ID 728579, 6 pages
Review Article

Cancers of the Appendix: Review of the Literatures

1New York Hospital Medical Center of Queens, Flushing, NY 11355, USA
2Nassau University Medical Center and North Shore LIJ Health System, East Meadow, NY 11554, USA
3Division of Hematology/Oncology, College of Physicians and Surgeons, Columbia University, New York, NY, USA

Received 24 May 2011; Accepted 26 June 2011

Academic Editor: Y. Akiyama

Copyright © 2011 Carl Ruoff et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the treatment remains controversial. Here we are reporting a 46-year-old male presented with symptoms of appendicitis, diagnosed with adenocarcinoma of the appendix. The patient was treated with appendectomy and refused further surgical intervention to complete hemicolectomy. Up to date, he remains asymptomatic. We performed literature review of the tumors of the appendix. Most of the benign conditions are treated with surgery alone. Lymphomas require CHOP-like chemotherapy and carcinoid syndrome treatment with somatostatin analogues. It is generally recommended that right hemicolectomy is the preferred treatment for adenocarcinoma of appendix. The role of chemotherapy is unclear due to lacking randomized trials but seems to be accepted if there is lymph node involvement or peritoneal seeding.