Table of Contents
ISRN Organic Chemistry
Volume 2011, Article ID 738361, 7 pages
http://dx.doi.org/10.5402/2011/738361
Research Article

Synthesis, Characterization, Thermal Properties, and Antimicrobial Activities of 5-(Diethylamino)-2-(5-nitro-1H-benzimidazol-2-yl)phenol and Its Transition Metal Complexes

Department of Intermediate and Dyestuff Technology, Institute of Chemical Technology (Formerly UDCT), N. P. Marg, Matunga, Maharashtra, Mumbai 400 019, India

Received 15 April 2011; Accepted 14 May 2011

Academic Editors: T. Kurtan, G. Li, and T. Ogiku

Copyright © 2011 Vikas S. Padalkar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Synthesis and antimicrobial activities of new metal [Co(II), Cu(II), Ni(II), and Fe(II)] complexes from 5-(diethylamino)-2-(5-nitro-1H-benzimidazol-2-yl)phenol are described. The newly synthesized ligands were characterized by IR, 1H NMR, and LC-MS analysis, and metal-ligand complex formations were confirmed by using atomic absorption spectroscopy and elemental analysis. All complexes show significant in vitro antibacterial activities against E. coli and S. aureus strains and in vitro antifungal activity against C. albicans and A. niger strains by using serial dilution method. The antibacterial activities were expressed as the minimum inhibitory concentration (MIC) in μg/mL. Thermal properties and electrochemical behavior of novel transition metal complexes have been studied.