Acute Pulmonary Embolism Decreases Adenosine Plasma Levels in Anesthetized Pigs

Table 1

Hemodynamics before and after gradual pulmonary artery embolism.

	Baseline	Embolism 1	Embolism 2	Embolism 3
Heart rate, bpm	90±8	122±8^a	135±9^a	148±8^ab
CO, L/min/m^2	4.1±0.1	3.3±0.4^a	2.7±0.3^a	1.7±0.3^abc
Psa, mmHg	110±10	119±11	106±8	88±8^abc
Ppa, mmHg	18±2	31±3^a	39±3^ab	47±4^abc
Pra, mmHg	7±1	7±1	9±2^ab	10±1^ab
Ppao, mmHg	7±1	7±1	11±1^ab	12±1^ab
Zo, dyn·s·cm^−5·m^2	530±45	1704±244^a	2268±190^ab	3498±208^abc
Zc, dyn·s·cm^−5·m^2	92±13	265±30^a	297±59^a	416±43^abc
F min, Hz	3.40±0.25	4.90±0.50^a	4.88±0.71	4.92±0.53^a
Ph1, rad	−0.32±0.03	−0.57±0.08^a	−0.55±0.09^a	−0.65±0.10^a
Ees, mmHg/mL	1.82±0.10	2.70±0.06^a	2.28±0.42^a	1.20±0.23^abc
Ea, mmHg/mL	1.08±0.15	3.15±0.13^a	4.22±0.40^ab	5.62±0.32^abc
Ees/Ea	1.69±0.15	0.86±0.28^a	0.54±0.25^a	0.21±0.07^abc
SV, mL

Values are means ± SE (). CO: cardiac output; Psa: systemic arterial pressure; Ppa: pulmonary arterial pressure; Pra: right atrial pressure; Ppao: occluded Ppa; Zo: 0-Hz impedance; Zc: characteristic impedance; Ees: end-systolic elastance; Ea: arterial elastance. versus baseline; versus embolism 1; versus embolism 2.