Table of Contents
ISRN Urology
Volume 2011 (2011), Article ID 786505, 7 pages
http://dx.doi.org/10.5402/2011/786505
Case Report

Small Cell Carcinoma of the Renal Pelvis: A Case Report and Review of the Literature

1Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ, USA
2Department of Surgery, Maulana Azad Medical College, New Delhi, India
3School of Medicine, Saint George’s University, Grenada
4Department of Surgery, University of Medicine and Dentistry of New Jersey, 94 Old Short Hills, Rd. Livingston, NJ 07039, USA

Received 16 February 2011; Accepted 12 March 2011

Academic Editors: A. C. Thorpe, K. H. Tsui, and M. S. Zaghloul

Copyright © 2011 Sachin Patil et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Extrapulmonary small cell carcinoma occurs in nearly all organs except the central nervous system and the liver. We are presenting a case of renal small cell carcinoma (SCC) with two unique characters. A 75-year-old patient was evaluated for back pain with no other complaints. Magnetic Resonance (MR) imaging of the abdomen revealed homogeneous tumor in the left renal pelvis extending beyond the kidney. Metastatic workup was negative. A left nephroureterectomy was performed. Histopathology and immunohistochemistry revealed a small cell carcinoma of the renal pelvis. The patient declined adjuvant therapy and died 2 months after surgery due to unrelated causes. After comprehensive worldwide literature search, we found 13 cases of SCC of the renal pelvis, including the current case. The mean age was 61.6 years (37–83), with a M : F ratio of 1 : 1.8. The average duration of symptoms was 71.4 days (21–168). Gross hematuria was the most common symptom (69.2%) followed by pain (61.5%). Adjuvant chemotherapy was provided to 4 patients (30.7%), and neoadjuvant to 1 patient. The median survival of patients who did and did not receive chemotherapy was 5.5 months (3–8) and 6 months (2–31), respectively, 𝑃 < . 5 0 . In conclusion, renal SCC (both parenchymal and pelvic SCC) is a rapidly fatal disease with a median survival of ≤8 months.