Autoantibodies to the -Adrenoceptor from Patients with Periodontitis as a Risk Factor for Cardiac Dysfunction
Figure 1
Immunoreactivity of circulating IgG antibodies against cardiac membrane (a) or against β 1-AR synthetic peptide (b). The optical density (OD) for serum sample (1/30 dilution) from 40 periodontitis patients (group I) or 20 normal individuals (group II) were evaluated by duplicate. Values are mean ± SD. Cutoff values of OD 0.180 and 0.210 for cardiac membranes and anti-β 1-AR synthetic peptide, respectively. Correlation (c) between titers of serum anti-β 1-AR peptide IgG and anticardiac membrane IgG from periodontitis patients. Anti-β 1-AR peptide IgG titters were plotted as function of anti cardiac membranes. The values correspond to 40 periodontitis patients.
