Table of Contents
ISRN Cardiology
Volume 2011, Article ID 804767, 3 pages
Case Report

Diffuse Involvement of Aorta in Patient with Familial Hyperlipidemia

1GATA Haydarpasa Research and Training Hospital, 81327 Istanbul, Turkey
2Erzurum Education and Research Hospital, 25700 Erzurum, Turkey
3Izmit Seka State Hospital, Izmit 41040, Turkey

Received 16 February 2011; Accepted 17 March 2011

Academic Editors: C. Baines, F. Cademartiri, and D. H. Glogar

Copyright © 2011 Mehmet Mustafa Can et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Familial hyperlipidemia (FH) is an inherited metabolic disorder caused by low-density lipoprotein (LDL) receptor abnormality. The delayed clearance of serum LDL results in severe hypercholesterolemia, which leads to the accumulation of LDL-derived cholesterol in skin, tendons, and arterial walls.In homozygous form of the disease, severely atheromatous involvement of the aorta extending to the coronary ostia is almost always present, and particular surgical strategy is required to prevent atheroembolic events.