Table of Contents
ISRN Endocrinology
Volume 2011, Article ID 810251, 5 pages
Research Article

Prevalence of Subclinical Hypothyroidism among Patients with Acute Myocardial Infarction

1Cardiology Clinic, Bağcılar Education and Research Hospital, Bagcilar, 34200 Istanbul, Turkey
2Internal Medicine Clinic, John F Kennedy Hospital, 34100 Istanbul, Turkey
3General Surgery Clinic, Bağcılar Education and Research Hospital, 34200 Istanbul, Turkey

Received 27 April 2011; Accepted 8 June 2011

Academic Editor: C. Bizzarri

Copyright © 2011 Okuyan Ertugrul et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. Subclinical hypothyroidism (SCH) is defined as a serum thyroid-stimulating hormone (TSH) level above the upper limit of normal despite normal levels of serum free thyroxine. There is growing evidence that SCH is associated with increased cardiovascular risk. We tried to investigate prevalence of SCH in acute myocardial infarction patients. Methods and Results. We evaluate free T3, free T4, and TSH levels of 604 patients (age 58.4) retrospectively, who have been admitted to the coronary intensive care unit between years 2004–2009 with the diagnosis of ST elevation (STEMI) or non-ST elevation acute myocardial infarction (NSTEMI). Mild subclinical hypothyroidism (TSH 4.5 to 9.9 mU/l) was present in 54 (8.94%) participants and severe subclinical hypothyroidism (TSH 10.0 to 19.9 mU/l) in 11 (1.82%). So 65 patients (10.76%) had TSH levels between 4.5 and 20. Conclusions. In conclusion, 65 patients (10.76%) had TSH levels between 4.5 and 20 in our study, and it is a considerable amount. Large-scale studies are needed to clarify the effects of SCH on myocardial infarction both on etiologic and prognostic grounds.