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International Scholarly Research Notices
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International Scholarly Research Notices
/
2011
/
Article
/
Tab 3
/
Research Article
Improving the Isotretinoin Photostability by Incorporating in Microemulsion Matrix
Table 3
Rate constants* of photodegradation for ITN in methanol solution and microemulsion (
𝑛
=
3
).
Drug
Sample matrix
K
𝑡
0
.
5
𝑅
2
ITN
Methanol solution
8
.
0
6
×
1
0
−
3
86
0.9830
Microemulsion
1
.
8
4
×
1
0
−
3
377
0.9899
formulation
∗
𝑡
is expressed in minutes.