Clinical Study
A Comprehensive Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease
Table 3
Changes of Actigraph, MMSE, HAM-D, WAIS-R, cerebral blood flow, and cerebrospinal fluid by rTMS (sham and real).
| | | Before rTMS | After sham rTMS | After real rTMS | value |
| Actigraph up state (1) | Mean counts per one minute | | | | 0.977 | | Resting (%) | | | | 0.611 | Actigraph down state (2) | Mean counts per one minute | | | | 0.652 | | Resting (%) | | | | 0.593 |
| MMSE | | | | | 0.114 | HAM-D | | | | | 0.447 |
| WAIS-R# | Verbal IQ | | | | 0.901 | | Performance IQ | | | | 0.159 | | Total IQ | | | | 0.742 |
| Cerebral blood flow | (ml/min/100 g) | | | | 0.078 |
| Cerebrospinal fluid## | Total protein (mg/dl) | | | | 0.579 | | HVA (ng/ml) | | | | 0.817 | | 5-HIAA (ng/ml) | | | | 0.799 | | MHPG (ng/ml) | | | | 0.368 | | NSE (ng/ml) | | | | 0.952 |
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Repeated measures ANOVA, *. #One-way ANOVA. ##Paired -test. (1): Actigraph record while awaken. (2): Actigraph record while sleeping. MMSE: Mini-Mental State Examination, HAM-D: Hamilton Depression Scale. WAIS-R: Wechsler Adult Intelligence Scale-Revised, IQ: intellectual quotient. HVA: homovanillic acid; 5-HIAA: 5-hydroxy indoleacetic acid; MHPG: 3-methoxy-4-hydroxyphenylethylene glycol. NSE: neuron-specific enolase.
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