Research Article

Studies on Wound Healing Activity of Heliotropium indicum Linn. Leaves on Rats

Table 4

Screening for wound healing activity of the methanol extracts of the selected plants (excision wound model) by inoculated with Stapphylococcus aureus.

Group TreatmentPercentage (%) wound closurePeriod of epithelialization (no. of days)
4th days6th days8th days11th days14th days16th days

IControl10 ± 1.2919.5 ± 2.3434 ± 3.8344.5 ± 5.7552 ± 4.5358.4 ± 5.8529.12 ± 2.65
IINitrofurazone (0.2% w/w)15.83 ± 6.2136.33 ± 2.98**59.5 ± 4.48**76.33 ± 4.91**90.5 ± 3.39**97.33 ± 1.97**18.03 ± 1.23**
IIIMethanol extract (HI)15.5 ± 1.433.5 ± 3.6**57.66 ± 3.84**63.16 ± 3.89**77.66 ± 3.71**93 ± 2.25**19.11 ± 0.88**

Values are expressed as mean ± S.E. ( 𝑛 = 6 ). All columns are significant using ANOVA.
* 𝑃 < . 0 5 , ** 𝑃 < . 0 1 when compared to control; Dunnet’s 𝑡 -test. (HI-H. indicum).