Research Article

Immunohistochemical Reactivity of the 14F7 Monoclonal Antibody Raised against N-Glycolyl GM3 Ganglioside in Some Benign and Malignant Skin Neoplasms

Table 1

Immunorecognition of 14F7 Mab in normal and non-malignant lesions of human skin.

SamplesNo. cases (%)Range intensityPositive cells

(i) Normal skin0/9 (0)0
(ii) Nevi
Benign melanocytic nevi2/11 (18,2) + / + + 3
 Dermal0/4 (0)0
 Junctional0/1 (0)0
 Compound2/6 (33,3) + / + + 3
 Displastic melanocytic nevi1/7 (14,3) + 1

Intensity: − negative, + weak, ++ moderate, +++ intense. Positive cells: 0 (negative to less than 5%), 1 (6–25%), 2 (26–50%) and 3 (more than 50%).