Systemic Lupus Erythematosus: Recent Concepts in Genomics, Pathogenetic Mechanisms, and Therapies

Table 1

Antibodies associated with various phenotypical presentations of lupus (adapted from [6]).

Phenotypical presentation	Typical autoantibody profile
Nephritis, photosensitivity, serositis	Anti-ds DNA
Photosensitivity	Anti-Ro/La
Neonatal lupus syndromes	Anti-Ro/La
Coagulopathy, thrombocytopenia, CNS syndromes	Lupus anticoagulant, antiphospholipid antibodies
Raynaud’s disease, myositis, and cardiopulmonary lesions	Anti-RNP
Drug-induced lupus	Antihistone