Research Article

Evaluation of Antihyperglycemic Activity of Citrus limetta Fruit Peel in Streptozotocin-Induced Diabetic Rats

Table 2

Hypoglycemic activity of different doses of MECL in normal rats.

GroupDoseBlood glucose level mg/dL
0th hour2 hour 30 min

Saline control5 mL/kg (p.o.) 7 9 . 6 2 ± 4 . 4 7 8 . 6 6 ± 1 . 4
MECL200 mg/kg (p.o.) 9 6 . 1 ± 1 . 0 1 * 8 7 . 7 ± 2 . 2 *
MECL400 mg/kg (p.o.) 9 7 . 3 ± 1 . 2 * 6 5 . 7 ± 4 . 2 *
Glibenclamide0.5 mg/kg (p.o.) 8 2 . 5 ± 1 . 4 * 7 7 . 8 3 ± 2 . 5 *

Values are expressed as mean ± SEM ( 𝑛 = 6 ); * 𝑃 < 0 . 0 0 1 compared with saline control group.