Evaluation of Antihyperglycemic Activity of Citrus limetta Fruit Peel in Streptozotocin-Induced Diabetic Rats

Table 4

Effect on body weight of different doses of MECL in normal and hyperglycaemic rats.

Group	Dose	Body weight in grams
		0th day	15 th Day
Saline control	5 mL/kg (p.o.)	176.16±7.51	197±5.8
STZ control	65 mg/kg (i.p.)	174.17±1.3 *	116.25±1.9 *
STZ + MECL	200 mg/kg (p.o.)	185.8±1.7 **	142±1.4 **
STZ + MECL	400 mg/kg (p.o.)	171.7±2.1 **	140.8±1.1 **
STZ + Glibenclamide	0.5 mg/kg (p.o.)	182.32±6.4 **	173.23±9.5 **

Values are expressed as mean ± SEM (𝑛=6); *𝑃<0.001 compared with saline control group and **𝑃<0.001 compared with STZ-control group.