Research Article

Optic Nerve and Spinal Cord Are the Major Lesions in Each Relapse of Japanese Multiple Sclerosis

Figure 1

Localization of each of 116 demyelinating attacks from 49 relapsing-remitting MS and NMO patients. 10.2% involved the cerebrum, 9.2% the brainstem, 26.9% the optic nerve, 32.4% the spinal cord, 10.2% involved complex lesions excluding the cerebrum and, 11.1% complex lesions including the cerebrum. Thus, only 21.3% of demyelinating attacks were localized in cerebrum and 78.7% were optic-spinal lesions, although the clinical phenotype showed that MS comprised 70% and NMO comprised 30%.