Optic Nerve and Spinal Cord Are the Major Lesions in Each Relapse of Japanese Multiple Sclerosis

<table>Localization of each of 116 demyelinating attacks from 49 relapsing-remitting MS and NMO patients. 10.2% involved the cerebrum, 9.2% the brainstem, 26.9% the optic nerve, 32.4% the spinal cord, 10.2% involved complex lesions excluding the cerebrum and, 11.1% complex lesions including the cerebrum. Thus, only 21.3% of demyelinating attacks were localized in cerebrum and 78.7% were optic-spinal lesions, although the clinical phenotype showed that MS comprised 70% and NMO comprised 30%.</table>

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Figure 1

Figure 1: Optic Nerve and Spinal Cord Are the Major Lesions in Each Relapse of Japanese Multiple Sclerosis 