International Scholarly Research Notices / 2011 / Article / Tab 1

Research Article

Optic Nerve and Spinal Cord Are the Major Lesions in Each Relapse of Japanese Multiple Sclerosis

Table 1

Clinical characteristics and initial symptoms of MS and NMO patients.

Characteristics Total of MS and NMOMSNMO
n = 78n = 55n = 23

Sex
 Male/female21 (27%)/57 (73%)15 (27%)/40 (73%)6 (26%)/17 (74%)
Age at onset, y.o.
 Mean ± SD35.3 ± 13.632.5 ± 13.0a41.9 ± 13.1a
Duration of disease, years
 Mean ± SD5.2 ± 7.06.0 ± 7.13.3 ± 6.3
EDSS
 Mean ± SD3.9 ± 2.53.9 ± 2.63.9 ± 2.2
Initial symptoms
 Sensory disturbance29%24%44%
 Visual loss26%27%22%
 Double vision or vertigo12%15%4%
 Acute motor weakness5%5%4%
 Chronic motor weakness5%7%0%
 Sphincter disturbance4%2%9%
 Ataxia1%2%0%
 Consciousness disturbance1%2%0%
 Complex17%16%17%

aMean age at onset of NMO patients was significantly older than that of MS patients (P = 0.005). Student’s t-test was used for the statistical analysis.