Clinical Study

Evaluating the Association between Assisted Conception and the Severity of Preeclampsia

Table 4

Analysis of preeclamptic disease severity: assisted versus unassisted conceptions.

VariableAssisted  % ( 𝑁 = 1 6 )Unassisted  % ( 𝑁 = 4 2 4 ) 𝑃 value

Severe disease100 (16)60.9 (258)0.0036
Systolic BP >16056.3 (9)78.8 (334)0.068
Diastolic BP >10537.5 (6)34.7 (147)0.97
IV BP medication25 (4)25.2 (107)0.79
Proteinuria ≥2+75 (12)35.4 (150)0.0031
Creatinine ≥1.050 (8)18.6 (79)0.0056
AST ≥4562.5 (10)20.3 (86)0.0002
ALT ≥6031.3 (5)11.3 (48)0.0441
Platelets <10025 (4)6.4 (27)0.0182
IUGR <10%50 (8)27.4 (116)0.09

Assisted pregnancies included use of clomiphene citrate, gonadotropins, IUI, IVF, ICSI, and donor egg,
Women with unassisted pregnancies did not report use of clomiphene citrate, gonadotropins, IUI, IVF, ICSI, or donor egg for conception.