Table of Contents
ISRN Obstetrics and Gynecology
Volume 2011, Article ID 929251, 5 pages
http://dx.doi.org/10.5402/2011/929251
Research Article

Body Mass Index Impacts In Vitro Fertilization Stimulation

1Eunice Kennedy Shriver National Institute of Child Health and Human Development, 10 Center Drive, Bethesda, MD 20892, USA
2Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, MD 20847, USA
3Department of Obstetrics and Gynecology, General Leonard Wood Army Community Hospital, 126 Missouri Avenue, MO 65473, USA
4Advanced Reproductive Medicine and Gynecology of Hawaii, 407 Uluniu Street, Suite 312, Kailua, HI 96734, USA

Received 19 August 2010; Accepted 18 October 2010

Academic Editor: E. Geva

Copyright © 2011 Micah J. Hill et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The objective of the study was to prospectively determine if body mass index (BMI) is predictive of live birth rates in patients undergoing IVF. The prospective study enrolled 117 infertility patients with the primary outcome measure being IVF success rates. Mean BMI did not differ between patients with successful outcomes and those without successful outcomes. There was a significant positive correlation between BMI and the number of stimulated follicles ( π‘Ÿ = 0 . 1 9 , 𝑃 < . 0 5 ). A significant negative correlation between BMI and ampules of gonadotropins used ( π‘Ÿ = βˆ’ 0 . 2 5 , 𝑃 < . 0 1 ) and between BMI and days of stimulation ( π‘Ÿ = βˆ’ 0 . 1 9 , 𝑃 < . 0 5 ) was noted. These data demonstrate that women with an elevated BMI produce more follicles, stimulate quicker, and require less gonadotropins during IVF. However, BMI did not have a significant effect on pregnancy outcome rates.