Figure 6: In vivo effect of FBPase and GS antisense cDNAs expression on tumor implantation of human glioma-derived cell line. Ten NMRI mice were irradiated by 6 Gy 24 hours before subcutaneous injection of 107 transfected cells. Tumor size was determined using a caliper square. Value represents the mean ± SEM, corresponding to 3 sets of transfection. 𝑃 < 0.001 versus empty plasmid, and statistical analysis was made using repeated ANOVA test for 10 mice. Data adapted from Blin et al. [100].