Clinical Study

Initial Stroke Severity Is the Major Outcome Predictor for Patients Who Do Not Receive Intravenous Thrombolysis due to Mild or Rapidly Improving Symptoms

Table 1

Characteristics of patients in the groups of favorable and unfavorable outcome.

FavorableUnfavorableP

No3217
Age, years64.7 ± 13.272.5 ± 10.00.037
Female sex10 (31.3)9 (52.9)0.138
Initial presentations
 NIHSS2.2 ± 2.15.7 ± 4.0< 0.001
 Improving symptoms*13 (40.6)14 (82.4)0.005
 Systolic BP, mmHg170 ± 26162 ± 260.261
 Diastolic BP, mmHg98 ± 1586 ± 180.018
 Glucose, mg/dL158 ± 64151 ± 500.724
Risk factors
 Atrial fibrillation1 (3.1)4 (23.5)0.043
 Artery stenosis7 (21.9)10 (58.8)0.012
 Hypertension23 (71.9)14 (82.4)0.417
 Diabetes9 (28.1)8 (47.1)0.185
 Previous stroke5 (15.6)4 (23.5)0.700
 Smoking habit14 (43.8)5 (29.4)0.327
Outcome at discharge
 NIHSS1.4 ± 1.35.3 ± 3.3< 0.001
 mRS1.2 ± 0.63.4 ± 0.5< 0.001
 Barthel index95.7 ± 8.457.7 ± 23.9< 0.001
Examinations
 MRA16 (50.0)12 (70.6)0.166
 Carotid duplex28 (87.5)17 (100.0)0.248
 MRA or duplex29 (90.6)17 (100.0)0.542
 EKG32 (100.0)17 (100.0)

*Number of patients excluded from thrombolysis due to improving symptoms. Continuous variables are median ± standard deviation.
Numbers in parenthesis denote percentage.