Table of Contents
ISRN Pharmaceutics
Volume 2011 (2011), Article ID 948314, 4 pages
http://dx.doi.org/10.5402/2011/948314
Research Article

Development and Validation of a HPLC and an UV Spectrophotometric Methods for Determination of Dexibuprofen in Pharmaceutical Preparations

Department of Pharmaceutical Analysis, JSS College of Pharmacy, Ootacamund, Tamilnadu-643 001, India

Received 12 April 2011; Accepted 16 May 2011

Academic Editors: G. N. C. Chiu and F. de la Calle

Copyright © 2011 Selvadurai Muralidharan and Subramania Nainar Meyyanathan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. A. Dionne and L. McCullagh, “Enhanced analgesia and suppression of plasma β-endorphin by the S(+)-isomer of ibuprofen,” Clinical Pharmacology and Therapeutics, vol. 63, no. 6, pp. 694–701, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. A. M. Evans, “Enantioselective pharmacodynamics and pharmacokinetics of chiral non-steroidal anti-inflammatory drugs,” European Journal of Clinical Pharmacology, vol. 42, no. 3, pp. 237–256, 1992. View at Google Scholar
  3. K. D. Rainsford, Pharmacology and Toxicology of Ibuprofen, Taylor & Francis, London, UK, 1999.
  4. A. D. Hulst, P. Augustijns, S. Arens et al., “Determination of artesunate by capillary electrophoresis with low UV detection and possible applications to analogues,” Journal of Chromatographic Science, vol. 34, no. 6, pp. 276–281, 1996. View at Google Scholar · View at Scopus
  5. J. Krzek, M. Starek, and D. Jelonkiewicz, “RP-TLC determination of S(+) and R(-) ibuprofen in drugs with the application of chiral mobile phase and UV densitometric detection,” Chromatographia, vol. 62, no. 11-12, pp. 653–657, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. P. D. Sethi, Identification of Drugs in Pharmaceutical Formulations by Thin Layer Chromatography, CBS Publisher, New Delhi, India, 1992.
  7. C. J. T. Thomas and S. Savage, “High-performance liquid chromatographic determination of ibuprofen in bulk drug and tablets,” Drug Development and Industrial Pharmacy, vol. 11, no. 5, pp. 1123–1131, 1985. View at Google Scholar · View at Scopus
  8. Y. Y. Lau, “Determination of ibuprofen enantiomers in human plasma by derivatization and high performance liquid chromatography with fluorescence detection,” Journal of Liquid Chromatography and Related Technologies, vol. 19, no. 13, pp. 2143–2153, 1996. View at Google Scholar
  9. H. Thomas Karnes, K. Rajasekharaiah, E. Ralph Small, and D. Farthing, “Automated solid phase extraction and hplc analysis of ibuprofen in plasma,” Journal of Liquid Chromatography and Related Technologies, vol. 11, no. 2, pp. 489–499, 1988. View at Google Scholar
  10. U. Mandal, A. Das, S. Agarwal et al., “Bioequivalence study of two formulations containing 400 mg dexibuprofen in healthy Indian subjects,” Arzneimittel-Forschung, vol. 58, no. 7, pp. 342–347, 2008. View at Google Scholar · View at Scopus
  11. “Q2A text on validation of analytical procedures,” in Proceedings of the International Conference on Harmonization (ICH '94), 1994.