The Characterization of the Repertoire of Wheat Antigens and Peptides Involved in the Humoral Immune Responses in Patients with Gluten Sensitivity and Crohn's Disease

Table 2

IgG antibody expressed as optical density (OD) against wheat and all gliadin, glutenin peptides, exorphins, gliadin-transglutaminase, transglutaminase, and WGA in healthy control subjects and patients with gluten sensitivity and Crohn’s disease.

	Wheat (OD)	𝛼-Gliadin 33 (OD)	𝛼-Gliadin 17 (OD)	𝛾-Gliadin 15 (OD)	𝜔-Gliadin 17 (OD)	Glutenin 21 (OD)	Gluteo-morphin (OD)	Pro-dynorphin (OD)	Gliadin + transglut (OD)	Transglut (OD)	WGA (OD)
Control mean ± SD	0.27±0.12	0.09±0.09	0.08±0.09	0.07±0.08	0.13±0.10	0.29±0.18	0.25±0.18	0.09±0.08	0.06±0.09	0.08±0.10	0.10±0.11
Gluten Sensitive Patient mean ± SD	0.45±0.38	0.18±0.37	0.38±0.53	0.62±0.60	0.37±0.52	0.55±0.52	0.35±0.49	0.64±0.57	0.40±0.50	0.85±0.76	0.36±0.66
𝑃 values	0.0155	0.1278	0.0053	0.0001	0.0167	0.0104	0.1565	0.0001	0.0013	0.0001	0.0314
Crohn’s patient Mean ± SD	0.71±0.57	0.23±0.35	0.22±0.36	0.47±0.53	0.26±0.43	0.29±0.39	0.24±0.34	0.59±0.58	0.34±0.43	0.63±0.65	1.00±1.06
𝑃 values	0.0005	0.0306	0.0341	0.0006	0.0692	0.4744	0.4621	0.0002	0.0021	0.0002	0.0002