Determination of Picogram Levels of Roxithromycin in Pharmaceutical, Human Serum, and Urine by Flow-Injection Chemiluminescence

Table 1

Comparisons of different methods for determination of ROX.

Methods	Linear range (μg mL^−1)	LOD (μg mL^−1)	References
HPLC	0.5–10.0	0.2	[6]
	0.05–20.0	0.05	[7]
	5.1–100.0	5.1	[8]
EC	4.2–84	0.4	[9]
FL	25.0–350.0	4.6	[10]
ATPSE	1.0–20.0	0.03	[11]
CE	0.02–201.0	7.0×10^−3	[12]
CL	1.0×10^−6-1.0×10^−3	3.0×10^−7	[13]
Proposed method	1.0×10^−7-1.0×10^−4	3.0×10^−8	This work