Clinical Study

Quick and Simple Evaluation of Sudomotor Function for Screening of Diabetic Neuropathy

Table 3

Association between ESC measurements in feet and clinical, biochemical and conventional neuropathic characteristics in type 2 diabetic patients.

ESC > 60 (μS)ESC 40 ≥ & ≤ 60 (μS)ESC < 40 (μS) 𝑃 value
( 𝑁 = 1 3 0 )( 𝑁 = 6 7 )( 𝑁 = 6 8 )

GenderM (74), F (56)M (38), F (29)M (37), F (31)
Age (yr)51.0 (11.5)53.0 (11.5)57.0 (10.5)<0.001
Duration of DM (yr)6.0 (10.0)8.0 (10.0)12.5 (10.5)<0.001
BMI (kg/m2)25.9 (5.1)26.7 (5.2)26.3 (5.3)0.88
Waist-hip ratio0.95 (0.09)0.96 (0.11)0.96 (0.11)0.43
Hemoglobin (gm%)12.5 (2.3)12.5 (1.9)12.1 (2.3)<0.01
Random glucose (mg%)169.0 (89.7)171.0 (99.5)159.0 (106.7)0.76
HbA1c (%)8.0 (2.0)8.3 (2.6)8.6 (2.7)<0.01
Uric acid (mg%)4.6 (1.7)4.6 (1.6)4.5 (1.5)0.42
Creatinine (mg%)0.7 (0.3)0.7 (0.2)0.8 (0.3)0.47
eGFR (mL/min/1.73 m2)111.0 (34.9)110.0 (38.3)97.2 (32.0)0.10
MNSI B score > 2 [n (%)]59 (45%)38 (56%)47 (69%)<0.01
VPT (Volts)11.5 (7.0)13.0 (6.5)15.0 (12.2)<0.001
Patients with all Ewing tests performed ( 𝑁 = 1 7 1 )875232
≥2 Abnormal Ewing test [n (%)]9 (10%)4 (8%)10 (31%)0.01

Values are median (IQR) or N (%). For continuous variables 𝑃 values are calculated using simple linear regression analysis, and for categorical variables using chi square proportion trend test in three ESC categories.