Reprogramming of Human Huntington Fibroblasts Using mRNA
Figure 5
Teratoma assay. NOD/LtSz-SCID/SCID mice were intramuscularly injected with 1 × 106 adult fibroblast-(factors: ONSTKM, Huntington donor, 56 years) derived mRNA-iPS cells and viral iPS cells together with Matrigel. After 8 weeks, the injected regions were dissected and stained with hematoxylin/eosin. Teratoma formations are detected in all analyzed tissues.
