Research Article

Effect of Echium amoenum Fisch. et Mey a Traditional Iranian Herbal Remedy in an Experimental Model of Acute Pancreatitis

Table 1

Effect of EAE extract on pathological scores of pancreas in cerulein-induced acute pancreatitis in mice.

GroupRouteEdemaLeukocyte infiltration

Shami.p.0.00.0
NegCtrli.p.2.6 ± 0.22.6 ± 0.2
EAE 100i.p.2.1 + 0.32.3 ± 0.3
EAE 200i.p.2.0 ± 0.32.1 ± 0.3
EAE 400i.p.1.3 ± 0.2*1.5 ± 0.2*

Sham: normal mice treated with normal saline, NegCtrl: negative control treated with normal saline, EAE: E. amoenum extract treated mice (100, 200, 400 mg/kg).
Data are shown as means ± SEM, n = 6 (Mann-Whitney U test).
* P < 0.05: significant difference compared to negative control group.