An Assessment of Epithelial and Mesenchymal Phenotypes in Experimental and Clinical Pulmonary Fibrosis
Changes in mesenchymal, epithelial, and apoptotic markers in IPF patients. RNA was isolated from surgical lung biopsies of IPF patients and qRT-PCR was performed to determine the expression of epithelial (a), mesenchymal (b), and apoptotic (c) regulated genes in normal, slow, and rapid progressors. Data points represent mean SEM of –10 for each group. *, ** significance versus normal control using Student’s t-test.
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