An Assessment of Epithelial and Mesenchymal Phenotypes in Experimental and Clinical Pulmonary Fibrosis

Figure 5

Changes in mesenchymal, epithelial, and apoptotic markers in IPF patients. RNA was isolated from surgical lung biopsies of IPF patients and qRT-PCR was performed to determine the expression of epithelial (a), mesenchymal (b), and apoptotic (c) regulated genes in normal, slow, and rapid progressors. Data points represent mean ± SEM of 𝑛=6–10 for each group. *𝑃<0.05, **𝑃<0.01 significance versus normal control using Student’s t-test.

(a)

(b)

(c)