Unusual Effects of Nicotine as a Psychostimulant on Ambulatory Activity in Mice

Figure 2

Effects of single subcutaneous administrations of 5–10 mg/kg of BUP (a), 2–4 mg/kg of MP (b), 0.031–0.125 mg/kg of HAL (c), or 0.625–0.25 mg/kg of FLU (d) on ambulatory activity in ICR mice. Results are shown using normalized values. Filled columns indicate mean values of total ambulatory activity for 60 min, and vertical lines indicate SEM. (a) 𝑁 = 40–120, (b) 𝑁 = 100–120, (c) 𝑁=18, and (d) 𝑁 = 16–18. *𝑃<0.05 compared with saline control.

(a)

(b)

(c)

(d)