Table of Contents
ISRN Allergy
Volume 2012 (2012), Article ID 183983, 9 pages
http://dx.doi.org/10.5402/2012/183983
Research Article

Clinical and Immunological Changes of Immunotherapy in Patients with Atopic Dermatitis: Randomized Controlled Trial

1Group of Clinical and Experimental Allergy, University of Antioquia, Medellin, Colombia
2Foundation for the Development of Medical and Biological Sciences (FUNDEMEB), Cartagena, Colombia
3Institute for Immunological Research, University of Cartagena, Cartagena, Colombia
4IPS Universitaria Sede Ambulatoria, Universidad de Antioquia Carrera 51A No. 62-42, Medellin, Colombia

Received 26 November 2011; Accepted 10 January 2012

Academic Editors: S. Burastero, A. Lorentz, B. M. Stadler, and B. Xu

Copyright © 2012 Jorge Mario Sánchez Caraballo and Ricardo Cardona Villa. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Bieber, “Atopic dermatitis,” New England Journal of Medicine, vol. 358, no. 14, pp. 1483–1494, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. A. S. Watanabe, L. A. M. Fonseca, C. E. S. Galvão, J. Kalil, and F. F. M. Castro, “Specific immunotherapy using Hymenoptera venom: systematic review,” Sao Paulo Medical Journal, vol. 128, no. 1, article 8, pp. 30–37, 2010. View at Google Scholar · View at Scopus
  3. J. Bousquet, R. Lockey, H. J. Malling et al., “Allergen immunotherapy: therapeutic vaccines for allergic diseases—A WHO position paper,” Journal of Allergy and Clinical Immunology, vol. 102, no. 4, pp. 558–562, 1998. View at Google Scholar · View at Scopus
  4. G. B. Pajno, L. Caminiti, D. Vita et al., “Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: a randomized, double-blind, placebo-controlled study,” Journal of Allergy and Clinical Immunology, vol. 120, no. 1, pp. 164–170, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. C. Bussmann, A. Böckenhoff, H. Henke, T. Werfel, and N. Novak, “Does allergen-specific immunotherapy represent a therapeutic option for patients with atopic dermatitis?” Journal of Allergy and Clinical Immunology, vol. 118, no. 6, pp. 1292–1298, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. U. Darsow, A. Wollenberg, D. Simon et al., “ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis,” Journal of the European Academy of Dermatology and Venereology, vol. 24, no. 3, pp. 317–328, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. J. M. Hanifin, “Diagnostic criteria for atopic dermatitis: consider the context,” Archives of Dermatology, vol. 135, no. 12, p. 1551, 1999. View at Google Scholar · View at Scopus
  8. L. Cox, B. Williams, S. Sicherer et al., “Pearls and pitfalls of allergy diagnostic testing: report from the American College of Allergy, Asthma and Immunology/American Academy of Allergy, Asthma and Immunology Specific IgE Test Task Force,” Annals of Allergy, Asthma and Immunology, vol. 101, no. 6, pp. 580–592, 2008. View at Google Scholar · View at Scopus
  9. N. J. Osborne, J. J. Koplin, P. E. Martin et al., “Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants,” Journal of Allergy and Clinical Immunology, vol. 127, no. 3, pp. 668–676, 2011. View at Publisher · View at Google Scholar
  10. R. Takiguchi, S. Tofte, B. Simpson et al., “Efalizumab for severe atopic dermatitis: a pilot study in adults,” Journal of the American Academy of Dermatology, vol. 56, no. 2, pp. 222–227, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Bussmann, L. Maintz, J. Hart et al., “Clinical improvement and immunological changes in atopic dermatitis patients undergoing subcutaneous immunotherapy with a house dust mite allergoid: a pilot study,” Clinical and Experimental Allergy, vol. 37, no. 9, pp. 1277–1285, 2007. View at Publisher · View at Google Scholar · View at Scopus
  12. R. Einarsson, S. Dreborg, L. Hammarstrom, T. Lofkvist, C. I. E. Smith, and G. Svensson, “Monitoring of mite Dermatophagoides farinae allergen-specific IgG and IgG subclass distribution in patients on immunotherapy,” Allergy, vol. 47, no. 2 I, pp. 76–82, 1992. View at Google Scholar · View at Scopus
  13. T. Werfel, K. Breuer, F. Ruéff et al., “Usefulness of specific immunotherapy in patients with atopic dermatitis and allergic sensitization to house dust mites: a multi-centre, randomized, dose-response study,” Allergy, vol. 61, no. 2, pp. 202–205, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. M. T. Glover and D. J. Atherton, “A double-blind controlled trial of hyposensitization to Dermatophagoides pteronyssinus in children with atopic eczema,” Clinical and Experimental Allergy, vol. 22, no. 4, pp. 440–446, 1992. View at Publisher · View at Google Scholar · View at Scopus
  15. Y. S. Kwon, S. H. Oh, W. H. Wu et al., “CC chemokines as potential immunologic markers correlated with clinical improvement of atopic dermatitis patients by immunotherapy,” Experimental Dermatology, vol. 19, no. 3, pp. 246–251, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Boquete, V. Iraola, M. Morales et al., “Seafood hypersensitivity in mite sensitized individuals: is tropomyosin the only responsible allergen?” Annals of Allergy, Asthma and Immunology, vol. 106, no. 3, pp. 223–229, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. L. Caraballo and N. Acevedo, “Allergy in the tropics: the impact of cross-reactivity between mites and ascaris,” Frontiers in Bioscience, vol. 3, pp. 51–64, 2011. View at Google Scholar
  18. N. Acevedo, J. Sánchez, A. Erler et al., “IgE cross-reactivity between Ascaris and domestic mite allergens: the role of tropomyosin and the nematode polyprotein ABA-1,” Allergy, vol. 64, no. 11, pp. 1635–1643, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. L. Cox, “Allergen immunotherapy and asthma: efficacy, safety, and other considerations,” Allergy and Asthma Proceedings, vol. 29, no. 6, pp. 580–589, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. C. Möller, S. Dreborg, H. A. Ferdousi et al., “Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-Study),” Journal of Allergy and Clinical Immunology, vol. 109, no. 2, pp. 251–256, 2002. View at Publisher · View at Google Scholar · View at Scopus
  21. G. B. Pajno, G. Barberio, F. R. De Luca, L. Morabito, and S. Parmiani, “Prevention of new sensitizations in asthmatic children monosensitized to house dust mite by specific immunotherapy. A six-year follow-up study,” Clinical and Experimental Allergy, vol. 31, no. 9, pp. 1392–1397, 2001. View at Publisher · View at Google Scholar · View at Scopus
  22. R. H. Alzakar and A. M. Alsamarai, “Efficacy of immunotherapy for treatment of allergic asthma in children,” Allergy and Asthma Proceedings, vol. 31, no. 4, pp. 324–330, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. R. E. Rossi, G. Monasterolo, C. Incorvaia et al., “Lack of neo-sensitization to Pen a 1 in patients treated with mite sublingual immunotherapy,” Clinical and Molecular Allergy, vol. 8, article no. 4, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. R. Van Ree, L. Antonicelli, J. H. Akkerdaas, M. S. Garritani, R. C. Aalberse, and F. Bonifazi, “Possible induction of food allergy during mite immunotherapy,” Allergy, vol. 51, no. 2, pp. 108–113, 1996. View at Google Scholar · View at Scopus
  25. J. Fernandes, A. Reshef, L. Patton, R. Ayuso, G. Reese, and S. B. Lehrer, “Immunoglobulin E antibody reactivity to the major shrimp allergen, tropomyosin, in unexposed Orthodox Jews,” Clinical and Experimental Allergy, vol. 33, no. 7, pp. 956–961, 2003. View at Publisher · View at Google Scholar · View at Scopus
  26. L. C. Grammer, M. A. Shaughnessy, and R. Patterson, “Modified forms of allergen immunotherapy,” Journal of Allergy and Clinical Immunology, vol. 76, pp. 397–401, 1985. View at Google Scholar · View at Scopus
  27. A. Ameal, J. M. Vega-Chicote, S. Fernández et al., “Double-blind and placebo-controlled study to assess efficacy and safety of a modified allergen extract of Dermatophagoides pteronyssinus in allergic asthma,” Allergy, vol. 60, no. 9, pp. 1178–1183, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Casanovas, J. Sastre, M. Fernández-Nieto, M. Lluch, J. Carnés, and E. Fernández-Caldas, “Double-blind study of tolerability and antibody production of unmodified and chemically modified allergen vaccines of Phleum pratense,” Clinical and Experimental Allergy, vol. 35, no. 10, pp. 1377–1383, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Casanovas, E. Fernández-Caldas, R. Alamar, and A. Basomba, “Comparative study of tolerance between unmodified and high doses of chemically modified allergen vaccines of Dermatophagoides pteronyssinus,” International Archives of Allergy and Immunology, vol. 137, no. 3, pp. 211–218, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. R. J. Rona, T. Keil, C. Summers et al., “The prevalence of food allergy: a meta-analysis,” Journal of Allergy and Clinical Immunology, vol. 120, no. 3, pp. 638–646, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. R. Sporik, D. J. Hill, and C. S. Hosking, “Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children,” Clinical and Experimental Allergy, vol. 30, no. 11, pp. 1540–1546, 2000. View at Google Scholar · View at Scopus