International Scholarly Research Notices

Clinical Study

The Risk Factors for Nosocomial Infection in Chinese Patients with Active Rheumatoid Arthritis in Shanghai

Table 1

Demographic, clinical characteristics and risk factors for nosocomial infection in RA patients.


Variable	Total patients	Infection	No infection	Univariate analysis	Multivariate logistic regression analysis
Variable			()	P value	Odds ratio (95%CI)	P value

Ages, mean (SD), years	59.81 (12.71)	59.66 (13.51)	58.69 (12.47)	0.113
Female, %	2034 (82.90)	476 (86.07)	1558 (82.04)	0.026	0.70 (0.53–0.92)	0.012
Course of diseases, median (IQR), years	9.00 (3.00–16.00)	9.00 (3.00–16.00)	9.00 (3.00–17.00)	0.344
Duration in hospital, mean (SD), days	11.49 (5.27)	12.31 (6.32)	11.25 (4.89)	<.001	1.03 (1.01–1.05)	<.001
Organs involved, No. mean (SD)	3.83 (0.67)	4.75 (0.79)	3.85 (0.63)	0.006	0.82 (0.72–0.93)	0.003
Comorbidities, No.mean (SD)	0.56 (0.81)	0.60 (0.81)	0.54 (0.80)	0.143
DMARDs, No. mean (SD)	1.90 (0.721)	2.00 (0.743)	1.87 (0.71)	<.001	1.22 (1.06–1.40)	0.005
Corticosteroids dosage, mean (SD), mg/d	3.55 (8.43)	4.33 (9.97)	3.31 (7.92)	0.027	1.02 (1.01–1.03)	0.003
Pulse CTX, %	95 (3.87)	31 (5.6)	64 (3.3)	0.017
Etanercept, %	1226 (50.00)	263 (47.56)	963 (50.71)	0.192
WBC counts, median (IQR), ×10⁹/L	6.40 (5.00–7.90)	6.60 (2.51–8.20)	6.38 (3.00–7.80)	0.005	1.04 (1.00–1.08)	0.051
PLT, median (IQR), ×10¹²/L	232.00 (173.00–302.00)	236.00 (171.00–306.00)	228.00 (174.00–302.00)	0.557
E., median (IQR), ×10⁹/L	0.14 (0.09–0.25)	0.14 (0.09–0.29)	0.14 (0.09–0.25)	0.013
HB, median (IQR), g/L	113.00 (102.00–125.00)	110.00 (100.00–122.00)	114.00 (103.00–126.00)	<.001
Globin, median (IQR), g/L	30.00 (27.00–34.50)	30.00 (26.00–34.00)	30.10 (27.00–34.60)	0.088
ALB, median (IQR), g/L	35.00 (30.00–39.20)	34.00 (28.00–38.00)	35.80 (31.00–40.00)	<.001	0.98 (0.97–0.99)	<.001
ESR, median (IQR), mm/H	36.00 (15.00–67.00)	38.00 (17.20–76.00)	36.00 (14.00–65.00)	0.006
CRP, median (IQR), mg/L	8.00 (2.53–28.10)	12.10 (.35–41.00)	7.88 (2.28–25.3)	<.001	1.03 (1.02–1.04)	0.021
IgG, median (IQR), mg/L	12.60 (4.76–16.00)	12.10 (6.80–15.70)	12.70 (2.80–16.00)	0.873
IgA, median (IQR), mg/L	2.68 (0.87–3.70)	2.74 (1.01–3.81)	2.60 (0.7–3.70)	0.356
IgM, median (IQR), mg/L	1.00 (0.20–1.64)	1.00 (0.40–1.56)	1.04 (0–1.67)	0.532

Data are number (%) of patients, unless otherwise indicated. SD: standard deviation. IQR: interquartile range. CI: confidence interval. Organs involved, No.: the number of involved organs. Comorbidities, No.: the number of comorbidities: hypertension, diabetes mellitus, malignancy, chronic lung disease, congestive heart failure, cardiac arrhythmia, renal failure, liver disease. DMARDs, No.: the numbers of DMARs (disease-modifying antirheumatic drugs). WBC: white blood cell. PLT: platelet. E: eosinophils. HB: homoalbumin. ALB: albumin. ESR: erythrocyte sedimentation rate. CRP: C-reactive protein.