Octanoylated Ghrelin Inhibits the Activation of the Palmitic Acid-Induced TLR4/NF-𝜿B Signaling Pathway in THP-1 Macrophages

Figure 3

Palmitic acid augmented the expression of IL-1β and TNF-α in THP-1 macrophages. (a) control; (b) palmitic acid 100 μmol/L group; (c) palmitic acid 200 μmol/L group; (d) palmitic acid 500 μmol/L; (e) LPS 10 ng/mL group. (A) Palmitic acid augmented the expression of TNF-α in a dose-dependent in THP-1 macrophages, with values expressed as mean ± SEM (*𝑃<0.05 versus control). (B) Palmitic acid augmented the expression of IL-1β in a dose-dependent in THP-1 macrophages, with values expressed as mean ± SEM (*𝑃<0.05 versus control).