Octanoylated Ghrelin Inhibits the Activation of the Palmitic Acid-Induced TLR4/NF-𝜿B Signaling Pathway in THP-1 Macrophages

Figure 4

Acylated ghrelin pretreatment decreased palmitic acid-induced level of TLR4 mRNA in THP-1 macrophages by real-time RT-PCR analysis. (a) control; (b) palmitic acid 200 μmol/L group; (c) ghrelin 1 nmol/L+palmitic acid 200 μmol/L group; (d) ghrelin 10 nmol/L+palmitic acid 200 μmol/L group; (e): Ghrelin 100 nmol/L+ palmitic acid 200 μmol/L group. Values are expressed as mean ± SEM (*𝑃<0.05 versus control; ^#𝑃<0.05 versus palmitic acid 200 μmol/L group).