International Scholarly Research Notices / 2012 / Article / Tab 1 / Review Article
Prognostic Significance of Vascular Endothelial Growth Factor Serum Determination in Women with Ovarian Cancer Table 1 Clinical and demographic characteristics of patients.
Author, year Tempfer et al., 1998 [21 ] Gadducci et al., 1999 [22 ] Chen et al., 1999 [23 ] Oehler and Caffier, 2000 [24 ] Cooper et al., 2002 [25 ] Li et al., 2004 [26 ] Harloziňska et al., 2004 [27 ] Hefler et al., 2006 [28 ] Mahner et al., 2010 [29 ] Origin and Dates 1990–1995 Austria 1990–1997 Italy 1992–1998 Taiwan Germany 1995–2000 Iowa 1999–2001 China 1997–2002 Poland 1990–2003 Austria, Iowa, Italy, Taiwan 1996–2004 Germany Number of cases 60 53 56 41 101$ 50 86 314 37 Age, mean or median* (range), years 55.6* (36–71) 59* (23–81) 52.5* (21–88) 62 (32–83) 64 (20–78) NA NA 59.9 58.61* (26–78) FlGO stage I 7 19 14 5
20
17 14 56 1 II 12 1 6 2 9 27 1 III 27 22 32 30
81
33 37 177 29 IV 14 11 4 4 26 46 6 Grade G1 21 17 21 NA
39
13 19 60 0 G2
39 12
35 NA 41 88 9 G3 24 NA
61 30 26 150 27 Epithelial ovarian cancer Serous 28 33 30 32
81 15 49 166 31 Mucinous 23 6 4 2 9 4 41 0 Undifferentiated 3 6 8 0 19 13 15 4 Endometrioid 3 7 10 7 0 20 39 1 Clear cell 2 0 4 0 0 0 0 9 1 Others 1 1 0 0 0 0 0 44 0 Nonepithelial ovarian cancer 0 0 0 0 0 7 0 0 0 Ascites >500 mL/presence** NA 21** NA NA 67** 22 64** NA 21 <500 mL/absence** NA 12** NA NA 34** 28 22** NA 15 Residual disease <2 or 1*** cm 38 9 40 11 68*** 44 32 164*** 22 >2 or 1*** cm 22 24 16 30 33*** 6 54 64*** 14 Lymph node involvement yes 23 NA NA NA NA 12 NA 38 10 no 37 NA NA NA NA 38 NA 63 11
$ : Cooper study contains a small group of peritoneal and fallopian tube malignant cancers; NA: not available data; *: Median values; **: Numbers of patients with presence/absence of ascites; ***: Numbers of patients with residual disease < or >1 cm.