Clinical Study
Biological Markers and Response to Neoadjuvant Taxane-Based Chemotherapy in Patients with Locally Advanced Breast Cancer
Table 2
Response of patients of locally advanced breast cancer to neoadjuvant chemotherapy according to biological prognostic factors.
| Variable |
Objective response () | No response () | P value | Number | % | Number | % |
| HmR status | | | | |
1 | HmR+ () | 59 | 77.6 | 15 | 78.9 | HmR− () | 17 | 22.3 | 4 | 21.1 |
Her2/neo status | | | | |
0.345 | Her2/neo+ () | 18 | 23.7 | 2 | 10.5 | Her2/neo− () | 58 | 76.3 | 17 | 89.5 | p53 status | | | | |
0.096 | Inactive p53 () | 20 | 26.3 | 9 | 47.4 | Intact p53 () | 56 | 73.7 | 10 | 52.6 |
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