Biological Markers and Response to Neoadjuvant Taxane-Based Chemotherapy in Patients with Locally Advanced Breast Cancer

Table 2

Response of patients of locally advanced breast cancer to neoadjuvant chemotherapy according to biological prognostic factors.

Variable	Objective response (𝑛=76)		No response (𝑛=19)		P value
	Number	%	Number	%
HmR status					1
HmR+; (𝑛=74)	59	77.6	15	78.9
HmR−; (𝑛=21)	17	22.3	4	21.1
Her2/neo status					0.345
Her2/neo+; (𝑛=20)	18	23.7	2	10.5
Her2/neo−; (𝑛=75)	58	76.3	17	89.5
p53 status					0.096
Inactive p53; (𝑛=29)	20	26.3	9	47.4
Intact p53; (𝑛=66)	56	73.7	10	52.6