International Scholarly Research Notices / 2012 / Article / Tab 5

Research Article

Application of HPLC for the Simultaneous Determination of Paracetamol, Chlorzoxazone, and Nimesulide in Pharmaceutical Dosage Form

Table 5

Accuracy studies for the determination of PCM, CHZ and NIM ( ).

Excess drug added to the analyte (%) Theoretical Content ( g mL−1)Measured conc. ± SDRecovery (%)% R.S.D. S.E.

PCM
80
40.95
41.27 ± 0.37
100.78
0.89 0.36
100
45.50
45.10 ± 0.45
99.12
0.99 0.40
120
50.05
49.95 ± 0.25
99.80
0.50 0.21

CHZ

80
47.25
47.45 ± 0.85
100.04
1.79 0.73
100
52.50
52.15 ± 0.97
99.33
1.86 0.76
120
57.75
58.05 ± 0.75
100.50
1.29 0.53

NIM

80
12.60
12.55 ± 0.15
99.60
1.19 0.49
100
14.00
14.05 ± 0.25
100.35
1.77 0.72
120
15.40
15.25 ± 0.10
99.02
0.65 0.27