Clinical Study
Left Ventricular Hypertrophy Is Associated with Diastolic Filling Alterations in Normotensive Offspring of Hypertensive Nigerians
Table 3
Comparison of offspring of hypertensive parents with and without left ventricular hypertrophy.
| | Parameter | LVH +ve | LVH −ve | value | | Mean (SD) | Mean (SD) |
| | Number | 12 | 53 | | | Age (years) | 21.4 (1.7) | 21.7 (2.5) | 0.7 | | BMI (Kg/m2) | 23.3 (1.6) | 21.8 (3.2) | 0.03* | | WC (cm) | 85.3 (8.0) | 78.8 (8.7) | 0.045* | | Pulse rate (beats/min) | 77.4 (10.3) | 75.8 (11.8) | 0.22 | | SBP (mmHg) | 122.5 (8.7) | 117.3 (8.9) | 0.068 | | DBP (mmHg) | 79.6 (5.0) | 74.7 (7.9) | 0.01* | | LAD (cm) | 3.39 (0.3) | 2.99 (0.45) | 0.002* | | Ejection fraction (%) | 61.3 (5.1) | 68.0 (8.5) | 0.01* | | Mitral E velocity (cm/s) | 73.7 (12.4) | 73.2 (12.7) | 0.9 | | Mitral A velocity (cm/s) | 36.3 (7.0) | 44.3 (9.8) | 0.004* | | Mitral E/A ratio | 2.1 (0.4) | 1.7 (0.4) | 0.01* | | Mitral DT (ms) | 263 (111) | 229 (96.1) | 0.4 | | IVRT (ms) | 105.3 (4.6) | 97.8 (7.5) | 0.13 | | PVF S wave (cm/s) | 48.4 (8.2) | 49.6 (8.7) | 0.24 | | PVF D wave (cm/s) | 46.0 (9.1) | 36.7 (11.9) | 0.01 | | PVF AR wave (cm/s) | 21.3 (5.6) | 25.6 (6.0) | 0.06 |
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Key: BMI: body mass index, WC: waist circumference, SBP: systolic blood pressure, DBP: diastolic blood pressure, LAD: left atrial dimension, DT: deceleration time, IVRT: isovolumic relaxation time, and PVF: pulmonary venous flow. *Statistically significant.
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