Table of Contents
ISRN Obstetrics and Gynecology
Volume 2012, Article ID 268218, 5 pages
http://dx.doi.org/10.5402/2012/268218
Clinical Study

Outcome of Fetuses with Diagnosis of Isolated Short Femur in the Second Half of Pregnancy

Clínica Morales, C/Trafalgar 46 10 2a, 46003 Valencia, 46023 Valencia, Spain

Received 18 November 2011; Accepted 3 January 2012

Academic Editors: A. Canellada and H. Rehder

Copyright © 2012 José Morales-Roselló and Núria Peralta LLorens. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives. To assess the outcome of fetuses with isolated short femur detected at 19–41 weeks and determine to what extent this incidental finding should be a cause of concern in fetuses with a normal previous follow-up. Methods. 156 fetuses with isolated short femur were compared with a control group of 637 fetuses with normal femur length. FL values were converted into ๐‘ -scores and classified into 4 groups: control group: ๐‘ -score over −2, group 1: ๐‘ -score between −2 and −3, group 2: ๐‘ -score between −3 and −4, and group 3: ๐‘ -score below −4. FL values were plotted with the curves representing ๐‘ -scores −2, −3, and −4. To assess fetal outcome, the frequency of SGA, IUGR, abnormal umbilical Doppler (AUD), Down’s syndrome, and skeletal dysplasia was determined for each group after delivery, and the relative risk in comparison with the control group was obtained. Finally, ROC curves were drawn in order to evaluate the FL diagnostic ability for the conditions appearing with increased frequency. Results. SGA, IUGR, and AUD were more frequent in the fetuses with short femur. Conversely, none of them presented Down’s syndrome or skeletal dysplasia. According to ROC analysis, FL measurement behaved as a good diagnostic test for SGA and IUGR. Conclusions. A short femur diagnosis in a fetus with an otherwise normal follow-up determines just a higher risk of being small (SGA or IUGR).